Anton Sokolov's Safehouse is a building atop Kaldwin's Bridge in which Anton Sokolov lives and where he conducts experiments to find a cure for the plague. Corvo Attano visits this place during The Royal Physician to kidnap Sokolov.
The safehouse features a wine cellar, a large lower level comprised of Sokolov's studio and some encased machines, an enclosed middle level containing a dining hall and a kitchen, and an upper level housing Sokolov's libraries and quarters. On the roof is a greenhouse where Sokolov often cages his human test subjects.
The immediate area around the safehouse is abandoned and derelict. The safehouse itself is separated from the street by a moat.
It is heavily guarded by both the City Watch and Overseers and has a few walls of light for protection, but the greenhouse has only one guard. One of Sokolov's paintings can be found on the first floor, and the house also has a whale oil-powered elevator, which connects the first level with the library. There are empty vials that can be filled with elixir in the greenhouse.
- The safehouse has a stone wall with an advertisement not usually found on houses, but on Dunwall's warehouses.
- Although Sokolov lives in the house there is no advanced laboratory equipment, suggesting that his main work is done elsewhere.
- The section of the bridge at which Sokolov's safehouse is located is called "North End".