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Piero's Spiritual Remedy.

Piero's Spiritual Remedy is the second of two anti-plague elixirs to have been created, the other being Sokolov's Elixir, and it is named for its creator, Piero Joplin. It is merged into the S&J Health Elixir. It is succeeded by the Addermire Solution.

When used by Corvo Attano and Daud, it revitalizes the mana required to perform their supernatural abilities. It restores 40% of max mana.

An editorial written by Piero attributes the mana-restoring power of the elixir to its ability to "revitalize the mind," as opposed to Anton Sokolov's, which only heals the body.

Related Bone Charms[]


  • Spirited I - Potions grant 5% more mana.
  • Spirited II - Potions grant 10% more mana.
  • Twist of Fortune I - Very rarely, using a potion grants full mana.
  • Twist of Fortune II - Sometimes, using a potion grants full mana.

The Knife of Dunwall and The Brigmore Witches[]

  • Spirited - Potions grant 10% more mana.


  • The restorative is also called simply Piero's Remedy in lore books and written notes.
  • According to the editorial written by Piero, he did not provide the name for his remedy.
  • It is hinted between Sokolov and Piero that the prime ingredient in the remedy is made from river krusts.
  • Posters advertising Piero's Spiritual Remedy note that it is "known to stop sickness and to improve the emotional energy of women" and "cures torpid liver and chest colds."
  • No remedies are found during the mission Dishonored. Only elixirs are found there, with the first remedies being found in the Void later on.