User blog comment:TheMightyTom99/Dishonored Achievement Ideas/@comment-1500935-20140125115317

I don't like achievements that forces me to mass murder enemies when the game offers me not to. And "genocide" is really not an appropriate word. Achievements based on gameplay are fun as long as they don't require you to repeat an action for more than 10 times, otherwise it's just a way for editors to make people play the s*** of their games.

For "Arcane Master", I don't think you can upgrade all powers and magic abilities in the game as there are not enough runes for that. "Gentleman" can be odd, if not misogynistic in a way, but that should be attributed to the neutralization of Lady Boyle instead of her assassination. "Man on a Mission" is a good idea, but there should be exceptions for important items, at least for Campbell's black book which has to be recovered during the second mission.

Since you did not mention exploration, I'd suggest those achievements:
 * Cartographer: collected all 9 rare maps.
 * To Future Generations: found all heirlooms in Dishonored.

Both the maps and heirlooms have a definite number in the game and can't be find twice, in a way similar to Sokolov's paintings, so that would make pretty hard achievements to get. Even now I'm not sure I found all heirlooms in both the game and its two DLC.