User blog comment:Essie Essex/Arkane Studios Announces Dishonored 2/@comment-27202257-20150615040025/@comment-5174994-20150615110324

For one, I don't see saves being carried over. With a generational jump like this, it would be unfair to only do this for people who played on PC. I could get it for PC if I wanted & then get the first one on PC too, but I'd rather just play the definitive edition, which appears to only be on consoles.

Secondly, I'm assuming the canon ending is the low chaos ending, in which it is implied that they did cure the plague.