Thread:MDGeistMD02/@comment-1500935-20140829233915/@comment-16241899-20140830063013

I've only played low chaos so far and did not poison the elixir still in either of my playthroughs, did not even go to Dr. Galvani to get the rat viscera. And on one of my playthroughs, I did only one mission for Slackjaw as well, since I had planned to kill the Pendletons anyway but wanted the key for the hotel. So yes, I can confirm that doing one side mission for each of them will trigger the confrontation in the sewers later.